EMIRA Members
Professor Bibek Gooptu
Professor Bibek Gooptu
Professor Bibek Gooptu
Professor of Respiratory Biology and Director, Centre for Fibrosis Research, University of Leicester
Consultant in Respiratory Medicine, Glenfield Hospital, University Hospitals Leicester
Interests: targetable disease mechanisms of inflammation and fibrosis. We study these at multiple scales, from molecules to tissues, approaching clinica
Professor of Respiratory Biology and Director, Centre for Fibrosis Research, University of Leicester
Consultant in Respiratory Medicine, Glenfield Hospital, University Hospitals Leicester
Interests: targetable disease mechanisms of inflammation and fibrosis. We study these at multiple scales, from molecules to tissues, approaching clinically-relevant questions from a structural biology perspective.
EMIRA Steering Group member
Dr Amanda Goodwin
Professor Bibek Gooptu
Professor Bibek Gooptu
Clinical Lecturer and Specialty Trainee (ST6) in Respiratory Medicine.
Interests: Understanding mechanisms of lung development and repair, cell-environment interactions, clinical research in ILD
EMIRA Steering Group member
Dr Katy Roach
Professor Bibek Gooptu
Dr Amanda Tatler
Lecturer in Respiratory Science, University of Leicester
Interests: Focused in the field of idiopathic pulmonary fibrosis (IPF) i) investigating the pro-fibrotic activities of human lung myofibroblasts and ii) assessing fibrotic responses and effects of pharmacological intervention in an ex vivo model of human lung fibrogenesis. With the a
Lecturer in Respiratory Science, University of Leicester
Interests: Focused in the field of idiopathic pulmonary fibrosis (IPF) i) investigating the pro-fibrotic activities of human lung myofibroblasts and ii) assessing fibrotic responses and effects of pharmacological intervention in an ex vivo model of human lung fibrogenesis. With the aim to understand the complexity of this disease and develop new innovative ways to study and treat IPF
EMIRA Steering Group member
Dr Amanda Tatler
Dr Beatriz Guillen Guio
Dr Amanda Tatler
Associate Professor, Lung Remodelling Group, University of Nottingham
Interests: Understanding the cellular and molecular mechanisms driving fibrosis and lung tissue remodelling in chronic lung diseases including ILDs. In particular, how matrix proteins, biomechanical signals and TGFb drive disease progression. Expertise include in vitr
Associate Professor, Lung Remodelling Group, University of Nottingham
Interests: Understanding the cellular and molecular mechanisms driving fibrosis and lung tissue remodelling in chronic lung diseases including ILDs. In particular, how matrix proteins, biomechanical signals and TGFb drive disease progression. Expertise include in vitro cell and molecular biology, ex vivo human tissue models and in vivo animal models of disease.
EMIRA Steering Group member
Dr Beatriz Guillen Guio
Dr Beatriz Guillen Guio
Dr Beatriz Guillen Guio
Wellcome Trust Sir Henry Wellcome Postdoctoral Fellow, University of Leicester
Interests: Investigating the genetic factors contributing to pulmonary fibrosis, acute respiratory distress syndrome (ARDS) and coronavirus disease 2019 (COVID-19), and exploring the potential genetic overlap between these phenotypes
EMIRA Steering Group member
Dr Harvinder Virk
Dr Beatriz Guillen Guio
Dr Beatriz Guillen Guio
Clinical Lecturer and Specialty trainee (ST5) in Respiratory Medicine, Glenfield Hospital
Interests: Overcoming barriers to clinical translation in ILD, with a specific focus on the tools used: antibodies, reproducibility and research integrity, genetically encoded biosensors, lentiviral-mediated genetic modification, patient-derived cel
Clinical Lecturer and Specialty trainee (ST5) in Respiratory Medicine, Glenfield Hospital
Interests: Overcoming barriers to clinical translation in ILD, with a specific focus on the tools used: antibodies, reproducibility and research integrity, genetically encoded biosensors, lentiviral-mediated genetic modification, patient-derived cell culture and alternatives to animal models. Co-leading regional clinical study: “Real world management and outcomes of acute exacerbations of ILD”. Looking to develop an ambitious cross-cutting portfolio of research.
Dr Richard Allen
Dr Rachel Clifford
Dr Richard Allen
Lecturer in Genetic Epidemiology, University of Leicester
Interests: Identifying genetic variants associated with progressive pulmonary fibrosis and multi-organ fibrosis through large-scale statistical analyses
Dr Samuel Cai
Dr Rachel Clifford
Dr Richard Allen
Lecturer in Environmental Epidemiology, University of Leicester
Interests: Understanding the impacts of indoor and outdoor air pollution, and other broader environmental factors such as temperature and greenspace exposures, on the development and progression of ILD
Dr Rachel Clifford
Dr Rachel Clifford
Dr Nicholas R.F. Hannan
Anne Mclaren Senior Research Fellow, University of Nottingham
Interests: Understanding cell type specific epigenetic regulation of gene expression in lung disease and cell free DNA methylation as a biomarker of disease, treatment response and disease mechanisms. Expertise include methylomics, tanscriptomics and in vitro cell and molecular biology
Dr Nicholas R.F. Hannan
Dr Nicholas R.F. Hannan
Dr Nicholas R.F. Hannan
Associate Professor of Translational Stem Cell Biology, University of Nottingham Biodiscovery Institute
Interests: Human induced pluripotent stem cell (hIPSC) models of lung development and disease, Gene Editing, IPF, Organoid and microtissue models of the lung, Inflammation and fibrosis
Dr Rob Hirst
Dr Nicholas R.F. Hannan
Professor Simon Johnson
Principal Scientist and Honorary Associate Professor, University of Leicester
Interests: Genetic discovery, diagnosis, understanding of primary human ciliopathies and the role of airway epithelial ciliary function in acute and chronic lung diseases.
Professor Simon Johnson
Dr Nicholas R.F. Hannan
Professor Simon Johnson
Professor of Respiratory Medicine, University of Nottingham and Honorary Consultant Physician.
Director of the National Centre for LAM
Interests: Tissue remodelling in chronic lung disease, protease and extracellular matrix, LAM and rare lung diseases
Dr Olivia Leavy
Professor Louise Wain
Dr Olivia Leavy
Research Associate in Genetic Epidemiology, University of Leicester
Interests: Genetic epidemiologist interested in understanding the role genetics has in the development of ILD
Dr Fasi Khan
Professor Louise Wain
Dr Olivia Leavy
Consultant Respiratory Physician, Glenfield hospital
Honorary Senior Lecturer, University of Leicester
Interests: Understanding the role of prognostic biomarkers in ILD; health (race) inequalities in ILD management; clinical research in ILD
Professor Louise Wain
Professor Louise Wain
Professor Louise Wain
Professor of Respiratory Research, University of Leicester
Interests: Genetic epidemiologist interested in identifying the genetic determinants of lung disease, and how we can use that information to drive our understanding of the underlying disease mechanisms to ultimately identify new treatments.